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Biopharmaceuticals: New Therapy Concepts in Oncology

The new biotech report describing the situation of medical biotechnology in Germany is now available. It was provided by The Boston Consulting Group for vfa bio. This yearly report is the only one recording all activities within medical biotechnology in Germany – ranging from startup to big companies. In addition to key economic data on medical biotechnology in Germany in 2016, the focus of this year’s report is on oncology.

Ärztin in weißem Kittel betrachtet Röntgenbilder einzelner Körperdurchschnitte.

This year's study focuses on new biopharmaceutical therapy concepts in oncology.

Overall, since the 1980s, 29 biopharmaceuticals—three-quarters of them monoclonal antibodies—have been approved with a first indication for the treatment of cancer. They are now a firmly established part of modern cancer therapy. Treatment for cancer currently comprises five pillars: surgery, radiation, chemotherapy, targeted therapies, and most recently, immuno-oncological therapies. The spending of German statutory health insurers on outpatient oncology products over the last five years averaged just 11.5% of their total drug spending, or only 2.2% of these insurers' total spending—this despite the fact that cancer is the second most frequent cause of death in Germany.

Pharmaceutical and biotech firms continue to invest intensively in oncology research, also pursuing completely new approaches like bi- or multispecific antibodies, glycomodified antibodies, antibody-drug conjugates (ADCs), mRNA- and DNA-based approaches, oncolytic viruses, and cell therapies. These new approaches are not yet able to overcome cancer, but they can help patients diagnosed with cancer live longer. More and more, cancer is becoming less a fatal disease than a chronic one.

To tap the large potential of medical biotechnology in Germany and realize medical advances, the industry needs stable and favorable frame conditions. These include reliable, innovationfriendly policies in health care systems, the ongoing expansion of basic research, the associated effective translation of ideas and insights in products and services, investments in research, development, and production in Germany, and a focus on value-based health care.

Development of 5 year survival rates in cancer

Cancer incidence increases but cancer related deaths do not